Thomas D. Brown Real Estate Associates
Rentals 508-349-2700
300 Route 6
PO Box 2003
Truro, MA 02666

388 Sea Street Hyannis Barnstable MA 02601 MLS #22602036

MLS #22602036 image #0
Just 800 feet from Keyes Memorial Beach and .7 miles by sidewalk to Main Street Hyannis, 388Sea Street is a rare coastal property with scale, flexibility, and proven rental appeal. Set on .45acres with two driveways and ample parking, this extensively renovated compound offers thekind of location that works beautifully for summer living, guest stays, hospitality use, or a mixedrental model.The property is anchored by a spacious main home, which includes 6 bedrooms and 4.5 baths,along with an attached 2 bedroom, 2 bath guest suite. Tucked into the lower rear side of thebuilding is a private studio unit with its own bath, adding another layer of flexibility. A separatetwo-car garage building completes the offering with a 1 bedroom, 1 bath apartment above.Altogether, the property offers approximately 4,525 square feet, 9 bedrooms, and 8.5 bathsacross several distinct living areas.Currently used as a successful hybrid blend of vacation rental and year-round rental housing, theproperty also holds an active lodging house license from the Town of Barnstable allowing up to10 individual rental rooms and a total of 20 people on site. Its Residential Congregate Housingzoning further supports a range of potential uses, including an inn, bed and breakfast, or continued operation as a flexible income-producing property.
The setting is the magic. Spend the day at Keyes Beach, head into downtown Hyannis for dinner, catch the ferries, explore the harbor, or simply enjoy the convenience of being close to so much of what makes Cape Cod such a compelling destination. For an investor, hospitality operator, or buyer seeking a substantial Hyannis property with rare permitted use, extensive renovations, and an exceptional near-beach location, 388 Sea Street is an offering with uncommon possibility.
Current real estate data for Single Family in Barnstable as of May 17, 2026
209
Single Family Listed
84
Avg DOM
621
Avg $ / SqFt
$1,906,430
Avg List Price

Property Details

Price:
$1,899,000
MLS #:
22602036
Status:
Active
Beds:
9
Baths:
8.5
Type:
Single Family
Subtype:
Single Family Residence
Listed Date:
May 7, 2026
Finished Sq Ft:
4,525
Total Sq Ft:
4,525
Lot Size:
19,602 sqft / 0.45 acres (approx)
Year Built:
1860
AntiqueBarnstable

Schools

School District:
Barnstable

Interior

Appliances
Dishwasher, Wine Cooler, Washer, Refrigerator, Electric Range, Microwave, Electric Dryer, Electric Water Heater
Bathrooms
8 Full Bathrooms, 1 Half Bathroom
Fireplaces Total
1
Flooring
Vinyl, Tile, Wood
Interior Features
Recessed Lighting, Pantry, Linen Closet
Laundry Features
Laundry Room, First Floor

Exterior

Architectural Style
Antique
Construction Materials
Shingle Siding
Exterior Features
Outdoor Shower
Garage Spaces
2
Lot Features
In Town Location, School, Medical Facility, House of Worship, Near Golf Course, Shopping, Marina
Open Parking YN
1
Parking Spots
12
Parking Total
12
Patio And Porch Features
Deck, Porch, Patio
Roof
Asphalt
Stories
3

Financial

Tax Year
2025
Taxes
$8,035

Map

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Property Summary

    388 Sea Street Hyannis Barnstable MA is a Single Family for sale in Barnstable, MA, 02601. It is listed for $1,899,000 and features 9 beds, 9 baths, and has approximately 4,525 square feet of living space, and was originally constructed in 1860. The current price per square foot is $420. The average price per square foot for Single Family listings in Barnstable is $621. The average listing price for Single Family in Barnstable is $1,906,430. To schedule a showing of MLS#22602036 at 388 Sea Street Hyannis in Barnstable, MA, contact your Thomas D Brown R E Associates agent at 508-487-1112.

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Raised in Orleans and now a resident of Truro, Lucy is extremely familiar with life on the Outer Cape. She is experienced in real estate sales on Cape Cod and has been involved in construction, development and real estate for over thirty-five years here on the Outer Cape. She presently handles all facets of marketing for both Brown Associates and Cape Vacation Rentals. Degree in Sales & Marketing; formerly associated with Nickerson Realty Corp. where she handled all phases of land development, a…

More About Lucy
388 Sea Street Hyannis
Barnstable, MA